BDBM50432563 CHEMBL2347011::US9115116, 8b
SMILES C[C@@H]1C[C@H](OC(=O)NCc2ccc(cc2)-c2cn(CCCCCCC(=O)NO)nn2)[C@@H]2[C@@H](CC[C@@H]3C[C@H](CC(=O)O3)O[Si](C)(C)C(C)(C)C)[C@@H](C)C=CC2=C1
InChI Key InChIKey=UYGBNWBNXHNKCQ-JKZGQAOVSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50432563
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
National Taiwan University
US Patent
National Taiwan University
US Patent
Affinity DataIC50: 53.8nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
National Taiwan University
US Patent
National Taiwan University
US Patent
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant HMG-CoA reductase (unknown origin) after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
National Taiwan University
US Patent
National Taiwan University
US Patent
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of HMG-CoA reductase in human A549 cells after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair